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Calcium: Improves Bone Health, Cardiac function, Kidney stones, cholesterol and More        

                              

 By Prof. Raphael Nyarkotey Obu

Calcium is the mineral the body has in abundance. It makes up the structures of your bones and teeth and also helps maintain typical muscle function, blood clotting, nerve transmission, and other body processes.

A study by Li et al.(2018) found that 99% of calcium in the body is found in the bones. Hence, the bones are like a calcium reservoir that the body seeks solace to restore balance.

Calcium can be found naturally in several foods, such as dairy products. Calcium-fortified foods are also readily available, and calcium supplements can help boost your calcium intake if needed.

For calcium to work effectively, the body has to be provided with vitamin D for proper absorption and maintenance of calcium levels. One needs a balance of both nutrients for the body to function well.

Calcium, science

An article by Rosalie Rung(2023) explained the following benefits: 

• Bone health: Calcium is critical for the development, health, and continued maintenance of bone. Women beyond menopause need calcium to maintain bone density and prevent osteoporosis.

• Blood clotting: Calcium plays a role in your blood’s ability to clot. While many chemicals and nutrients are involved, calcium is an important factor.

• Cardiac function: Calcium helps maintain the action of your heart muscle by relaxing the smooth muscles around your blood vessels. Calcium has also been linked to lower blood pressure(Lin et al. 2008). 

The reason has been linked to the DASH diet (Dietary Approaches to Stop Hypertension) recommends a diet high in calcium-rich foods like yogurt or kefir because these are foods that help improve blood pressure. The natural fat found in dairy products has been shown to have certain benefits, so full-fat dairy is recommended over low-fat dairy.

• Muscle contraction: Calcium can help balance muscle contraction. Calcium is released when a muscle is stimulated. This helps the muscle contract. When the calcium is pumped out of the muscle, it can relax.

• Preventing preeclampsia: Consuming certain amounts of calcium during pregnancy can aid in lowering blood pressure, reducing the risk of preeclampsia.

• Improved cholesterol levels: Calcium is also known to help improve certain cholesterol levels in the blood.

• Cancer:  Studies explained that consuming calcium-rich foods is linked to a decreased risk of certain types of cancer, particularly colon and rectal cancers. For instance, the American Cancer Society’s Cancer Prevention Study II Nutrition Cohort study revealed that men and women who had the highest intakes of calcium through both their diets and supplements had a reduced risk of colorectal cancer compared with those who had the lowest calcium intakes.

As it stands,  evidence is not currently strong enough to recommend calcium supplements for the prevention of colon cancer, but eating foods with calcium may have the same effect.

• Weight Health: Bendsen et al.(2008) study found a link between higher calcium intake from foods high in calcium and lower body weight.  The reason is that calcium in the diet can bind to fat in the digestive system, helping it be excreted and possibly preventing some fat absorption, therefore helping lower the amount of calories that contribute to fat gain.

Calcium, Dosage

The amount of calcium needed depends on the age and stage of life. National Institutes of Health Office of Dietary Supplements(2024) provided the following recommended dietary allowance (RDA) of calcium in milligrams (mg):

It is instructive to note that calcium both males and females have the same need for calcium before the age of 50 years. Females need however increase slightly. Females need more calcium level especially in their pregnancy stage as it decreases the risk of preeclampsia. Preeclampsia is defined as hypertension and proteinuria or thrombocytopenia during pregnancy, usually after 20 weeks gestation  (Leeman et al. 2016). 

It is a leading cause of maternal and neonatal morbidity and mortality that affects about 4% of pregnancies in the United States  (Ananth et al. 2013).

National Institutes of Health Office of Dietary Supplements(2024) revealed that Calcium deficiencies happen as a result of a reduction in the calcium level in the blood (your serum calcium level) below 8.5 milligrams per deciliter (mg/dL).

When the reduction is drastic you will experience the following symptoms of a calcium deficiency:

• muscle spasms

• depression

• confusion

• muscle cramps

• hallucinations

• weak and brittle nails

• easy bone fractures

• seizures

some health conditions or life changes could affect calcium deficiency. These can include:

• menopause

• hypoparathyroidism

• malnutrition or malabsorption

• pancreatitis

• septic shock

• certain medications, including steroids and some chemotherapy drugs

• kidney failure

• lack of a parathyroid gland (due to surgery)

• frequent blood transfusions

Calcium foods

Calcium is naturally found in many foods. However, dairy products are the best-known source of calcium, other nondairy foods can also contain high calcium levels.

 calcium-rich foods include:

• yogurt

• milk

• cheese

• sardines and salmon

• fortified nondairy milk (soy milk)

• nuts and seeds

• tofu

• kale

• legumes (beans)

• fortified juices and cereals

Vegetables that contain calcium but have high oxalic acid levels, such as spinach, may reduce your body’s ability to absorb calcium.

Calcium supplements?

Li et al.(2018) explained that calcium supplements are ideal for those who are not getting enough. 

The amount of calcium in supplements varies, but most supplements contain between 300 and 500 mg of calcium. Vitamin D is most often added to help in proper absorption.

The two most common forms of calcium in supplements are calcium carbonate and calcium citrate. Each of these forms contains different amounts of elemental calcium, which is the actual amount of calcium in the supplement. Calcium carbonate is 40% calcium by weight, whereas calcium citrate is 21% calcium by weight.

Irrespective of the type you are taking, you should take it with food for the highest absorption, and doses are in the amount of 500 mg or less.

Calcium, warning

Few minor side effects such as gas, constipation, bloating, or a combination of these symptoms had been found. You can reduce the dose or switch to a different supplement if you find any side effects. 

Abundant calcium levels (hypercalcemia) are rare in the general population, however, it could result from conditions such as cancer or primary hyperparathyroidism.

Those with highly elevated calcium levels could experience:

• poor muscle tone

• constipation

• kidney issues

• low phosphate levels (hypophosphatemia)

• excessive urination

• nausea

• fatigue

• higher risk of death from cardiovascular disease

• unexplained weight loss

• irregular heart rhythms (arrhythmia)

Calcium tends to also interact with some drugs. When this happens, it could cause the drugs not to work well, or the drugscould affect the amount of calcium in the body.

The following are drugs shown to interact with calcium according to Healthline:

• Levothyroxine: This drug is prescribed to treat hypothyroidism or thyroid cancer. Calcium carbonate supplements can prevent its absorption, so you should not take them within 4 hours of taking levothyroxine.

• Lithium: Commonly used to treat bipolar disorder, long-term lithium use can result in hypercalcemia. Taking calcium supplements in addition to lithium can increase this risk.

• Dolutegrevir: Used in HIV treatment, taking calcium supplements along with dolutegrevir can reduce the effectiveness of the medication. Careful timing of calcium supplements is recommended for people taking dolutegrevir.

• Quinolone antibiotics: Calcium supplements are known to reduce the effectiveness of this class of antibiotic medication. Any calcium supplements should be taken at least 2 hours before or after this medication.

Take Home

There are many calcium supplements on the market, each of which varies based on the type of calcium, dosage, and ingredients it contains.

When selecting a calcium supplement, be sure to consider all of these factors and look for products that have undergone third-party testing to ensure that you’re getting the highest quality possible.

Also, the type is important. For instance, Calcium carbonate is more widely available and cheaper, and it contains a higher amount of calcium. But it could trigger gas and bloating(Li et al. 2018). Calcium citrate is more expensive but more easily absorbed in the body, which may be key for people who have low stomach acid or are taking proton pump inhibitors.

Also, it is important to check the ingredient label carefully and avoid products that have high amounts of fillers, additives, artificial sweeteners, and preservatives. Most products also contain added ingredients like vitamin D, which can help in the absorption of calcium(Wimalawansa et al. 2018). 

Finally, calcium requirements range from 1,000–1,300 mg daily for most adults, supplements with 200–500 mg are usually enough to help fill in the gaps in your diet. Some will need a higher amount, such as those with certain dietary restrictions or health conditions.

Also one large study(Balk et al. 2017) across 74 countries, found that the average national dietary calcium intake ranged from 175 to 1233 milligrams/day.

Compared to other minerals, we need a higher amount of calcium each day — making foods high in calcium very important for several reasons. We are told to have enough calcium in our bodies to constitute 2 percent of our total body weight, failure-prone to the following;

• Higher chance of developing osteopenia or osteoporosis

• Tooth decay

• Bone fractures

• Muscle tension

• High blood pressure

• Hardening of the arteries and hypertension

• Inflammation

• PMS symptoms

• Indigestion

• Higher risk for kidney stones and gallstones

• Higher risk for heart disease and diabetes

• Higher risk for certain types of cancer

NB:

Prof. Nyarkotey has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations to justify his write-ups. My articles are for educational purposes and do not serve as Medical advice for Treatment. I aim to educate the public about evidence-based scientific Naturopathic Therapies.

The writer is a Professor of Naturopathic Healthcare, a Medical Journalist, and a science writer. President, NyarkoteyUniversity College of Holistic Medicine & Technology (NUCHMT)/African Naturopathic Foundation, Ashaiman, Ghana. E. mail: professor40naturopathy@gmail.com. Visit-profnyarkotey.com for more. 

Author- “Life in the Gambia-Tales from a Professor and an Aspiring Barrister.”

 

References

1. Li K, Wang XF, Li DY, Chen YC, Zhao LJ, Liu XG, Guo YF, Shen J, Lin X, Deng J, Zhou R, Deng HW. The good, the bad, and the ugly of calcium supplementation: a review of calcium intake on human health. Clin Interv Aging. 2018 Nov 28;13:2443-2452. doi: 10.2147/CIA.S157523. PMID: 30568435; PMCID: PMC6276611.

2. Leeman L, Dresang LT, Fontaine P. Hypertensive disorders of pregnancy. Am Fam Physician 2016;93:121-7. 

3. Ananth CV, Keyes KM, Wapner RJ. Pre-eclampsia rates in the United States, 1980-2010: age-period-cohort analysis. Bmj 2013;347:f6564. 

4. Wimalawansa SJ, Razzaque MS, Al-Daghri NM. Calcium and vitamin D in human health: Hype or real? J Steroid Biochem Mol Biol. 2018 Jun;180:4-14. doi: 10.1016/j.jsbmb.2017.12.009. Epub 2017 Dec 16. PMID: 29258769.

5. Bendsen NT, Hother AL, Jensen SK, Lorenzen JK, Astrup A. Effect of dairy calcium on fecal fat excretion: a randomized crossover trial. Int J Obes(Lond). 2008 Dec;32(12):1816-24. doi: 10.1038/ijo.2008.173. Epub 2008 Oct 7. PMID: 18838979.

6. Lin PH, Ginty F, Appel LJ, Aickin M, Bohannon A, Garnero P, Barclay D, Svetkey LP. The DASH diet and sodium reduction improve markers of bone turnover and calcium metabolism in adults. J Nutr. 2003 Oct;133(10):3130-6. doi: 10.1093/jn/133.10.3130. PMID: 14519796.

7. Balk, E.M., Adam, G.P., Langberg, V.N. et al. Global dietary calcium intake among adults: a systematic review. Osteoporos Int 28, 3315–3324 (2017). https://doi.org/10.1007/s00198-017-4230-x

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